Dosis Koomposisi Eksedryl Expectorant

EKSEDRYL EXPECTORANT
eksedryl ekspektoran obat batuk berdahak
Informasi Obat Eksedryl Expectorant Syrup. Komposisi, Indikasi, Cara Kerja Obat, Dosis, Peringatan dan Perhatian, Efek Samping, Kontra Indikasi, Interaksi Obat, Kemasan dan Harga.
Composition
Each teaspoon ( 5 ml ) contains :
Diphenhydramine HCl   : 13,5 mg
Ammonium Chloride     : 131,5 mg
Sodium Citrate             : 55 mg
Alcohol                        : 2,5%

Drug class and mechanism
Diphenhydramine is an antihistamine with anticholinergic ( drying ) and sedative properties that is used to treat allergic reactions. Histamine is released by the body during several types of allergic reactions and to a lesser extent during some viral infections, such as the common cold. When histamine binds to its receptors on cells, it causes changes within the cells that lead to sneezing, itching,and increased mucus production. Antihistamines compete with histamine for cell receptors ; however , when they bind to the receptors they do not stimulate the cells. In addiction, they prevent histamine from binding and stimulating the cells. Diphenhydramine  was originally approved by the FDA in 1946.

Indications
For the relief of nasal and non-nasal symptoms of various allergic conditions such as seasonal allergic rhinitis.

Dosage
Adults        : 2 teaspoons, 3 – 4 times daily
Children    : 1 teaspoon, 3 – 4 times daily

Warning and Precautions

•  During  the administration of this drug, the patients are not allowed to drive or operate machinery.
•  Careful to the patients with the history of : lower respiratory disease, including asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease or hypertension. Narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, symtomatic prostatic hypertrophy, or bladderneck obstruction.
•  Usage in pregnant women and children under 6 years old only under doctor’s prescription.
•  May cause drowsiness and has an additive effect with alcohol.
•  Do not administer this drug to patient under antidepresant drug treatment ( Mono Amina Oxidase ).
•  Do not exceed indicated dose.

Side Effects
Can commonly cause sedation, unconciousness, dizziness, disturbed coordination, drying and thickening of oral and other respiratory secretions, and stomach distress.

Contraindications

•  Sensitive to Diphenhydramine
•  Premature baby
•  Lactating women

Drug Interactions
May cause additive effect to hypnotic and tranquilizer drugs.

Presentation
Bottle of 60 ml
Botle of 120 ml
Reg. No. DTL8306701137A1

STORE AT TEMPERATURE ( 25 – 30 C ) AND DRY PLACE, PROTECT FROM LIGHT
KEEP THE CONTAINER TIGHTLY CLOSED AFTER EACH USE

MAY CAUSE DROWSINESS

Manufactured by :
 PT SOHO INDUSTRI PHARMASI
Jakarta – Indonesia

For        :
PT ETHICA
Jakarta – Indonesia

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